Molecular Tools
There are various molecular tools, such as RNA interference (RNAi), Microarrays, and Chemical Genetics, to investigate the function of our desired Proteins.
RNAiA technique to silence gene expression by using double-stranded RNAs
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MicroarraysA technique to measure the large number of gene expression levels simultaneously
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Chemical GeneticsA technique to modify or disrupt the function of activity of specific proteins and biological processes by using small molecules
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References
- RNAi Database sample wiki. (n.d.). - DolceraWiki. Retrieved May 19, 2014, from http://www.dolcera.com/wiki/index.php?title=RNAi_Database_sample_wiki
- File:DNA microarray.svg. (n.d.). - Wikimedia Commons. Retrieved May 19, 2014, from http://commons.wikimedia.org/wiki/File:DNA_microarray.svg
- Dr Richard Foster | The Astbury Centre for Structural Molecular Biology. (n.d.). Dr Richard Foster | The Astbury Centre for Structural Molecular Biology. Retrieved May 19, 2014, from http://www.astbury.leeds.ac.uk/people/staff/staffpage.php?StaffID=RF
- DNA microarray. (2014, November 5).Wikipedia. Retrieved May 19, 2014, from http://en.wikipedia.org/wiki/DNA_microarray
- Norambuena, L., Hicks, G.R., & Raikhel, N.V. (2009). The Use of Chemical Genomics to Investigate Pathways Intersecting Auxin-Dependent Responses and Endomembrane Trafficking in Arabidopsis Thaliana. Methods Mol Biol, 495, 133-143.